Papains
Supplier: EGV-FritzTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
For digestion of the extracellular matrix of cartilage.
- Degrades protein substrates more effectively than other pancreatic proteases, while minimizing cell damage
Degrade protein substrates effectively while minimizing cell damage with Papain. This cysteine protease has a wide specificity, but has a preference for arginine, lysine, and phenylalanine. Native crystalline papain is unreactive until acted upon by mild reducing agents, e.g., cysteine, sulfide, or sulfite, and therefore likely exists as a zymogen. Compared to other pancreatic proteases, this enzyme facilitates more extensive degradation of protein substrates, such as the intercellular matrix proteins in cartilage. It is typically less damaging and more effective than other proteases for tissue dissociation applications (Huettner and Baugham; Lam). Papain has also been used for the digestion of neural tissue (Fasano et al.).
Caution: Product Restrictions: (i) Customer shall not make products or any portion of them, in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier; and (ii) Customer is familiar with Supplier's restrictions on the use of the Products and shall use the Products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').
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