Anti-Beta-Tubulin III Mouse Monoclonal Antibody [clone: 2G10-TB3]

Supplier: Stemcell Technologies
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60092 60092.1
MSPP-60092EA 581.69 USD
MSPP-60092 MSPP-600921
Anti-Beta-Tubulin III Mouse Monoclonal Antibody [clone: 2G10-TB3]
Antibodies
Mouse monoclonal IgG2a antibody against human, mouse, rat beta-tubulin III, unconjugated.

  • Neural cells Psc Derived
  • Neurons

The 2G10-TB3 antibody reacts with beta-tubulin III, an ~50 to 55 kDa structural protein that is a constituent of tubulin. Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha- and beta-tubulin subunits. The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types. Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation. It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells. The 2G10-TB3 antibody is expected to recognize all mammalian homologs of beta-tubulin III and the epitope has reportedly been mapped to the extreme C-terminal amino acids, EAQGPK.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-Beta-Tubulin III Mouse Monoclonal Antibody [clone: 2G10-TB3]
Antigen: Beta-Tubulin III
Clonality: Monoclonal
Clone: 2G10-TB3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human, Mouse, Rat
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