Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (CF594) [clone: B22.1 B23.1]

Supplier: Biotium
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BNC941221-100 BNC941221-500
75920-700EA 205.77 USD
75920-700 75920-702
Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (CF594) [clone: B22.1 B23.1]
Antibodies
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: KRT8 & KRT18
Clonality: Monoclonal
Clone: Clone B22.1 B23.1
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
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