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Supplier: Biotium

Description: GelRed™ and GelGreen™ are a new generation of fluorescent nucleic acid gel stains designed to replace the highly toxic ethidium bromide (EtBr)

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Supplier: Biotium

Description: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Supplier: Biotium

Description: CD90 Monoclonal antibody, Clone: F15-42-1-5, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Purified human brain Thy1Unigene 644697, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Supplier: Biotium

Description: S100A9, Monoclonal antibody, Clone: 47-8D3, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgM, Conjugate: purified, Immunogen: Human peripheral blood monocyte components, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Supplier: Biotium

Description: This antibody neutralizes TNF alpha biological activities. It prevents TNF alpha induced apoptosis in Jurkat cells. It also neutralizes HurTNFamediated cytotoxicity of L929 cells and inhibits tumor growth in mice. It protects mice against toxicity of HurTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.

Supplier: Biotium

Description: FOXP3 Monoclonal antibody, Clone: 3G3, Host: Mouse, Species reactivity: Mouse, Monkey, Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Full-length His-tagged mouse FOXP3 protein, Application: Immunofluorescence, Flow cytometry, Size: 500 uL

Supplier: Biotium

Description: This conjugate is prepared by labeling F(ab’)2 fragment of goat anti-rabbit IgG (H+L) with CF™640R dye. CF™ dyes offer advantages in brightness, photostability, and specificity compared to other fluorescent dyes. Far-red fluorescent CF™640R (Ex/Em 642/662 nm) is much brighter than Cy®5 and at least as bright as Alexa Fluor® 647, and has exceptional photostability.

Alexa Fluor® is a registered trademark of Thermo Fisher Scientific. Cy®5 is a registered trademark of GE Healthcare.

Supplier: Biotium

Description: CD74 Monoclonal antibody, Clone: BU45, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: B lymphoblastoid cell line HFB1Unigene 436568, Application: Immunofluorescence, Western, Flow cytometry, Size: 500 uL

Supplier: Biotium

Description: Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier: Biotium

Description: CD37 Monoclonal antibody, Clone: IPO-24, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Immunogen: Spleen cells of a patient with hairy cell leukemia, Isotype: IgG2b, kappa, Synonyms:Cell differentiation antigen 37, Application: IF, FC, Size: 100uL

Supplier: Biotium

Description: TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF594, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL

Supplier: Biotium

Description: Calponin-1 Monoclonal antibody, Clone: CALP, Host: Mouse, Species Reactivity: Human, Rat, Isotype: IgG's, Conjugate: CF568, Immunogen: Multiple isoelectric variants of calponin of 34kDa and a 29kDa, Synonym: Cnn1, Sm Calp, SMCC, Calponin-1, Application: IF, IHC, FC, Size: 500ul

Supplier: Biotium

Description: This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier: Biotium

Description: CD79A Monoclonal antibody, Clone: IGA/764, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recombinant human IGA protein, Application: IF, Immunohistology (formalin), FC, Size: 500 uL

Supplier: Biotium

Description: PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: PTH/1174, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF647, Immunogen: synthetic peptide from N-terminal of PTH polypeptide, Synonyms: Parathyrin, Size: 100uL

Supplier: Biotium

Description: Cytokeratin 8/18 Monoclonal antibody, Clone: C-51, Host: Mouse, Species reactivity: Human, Monkey, Pig, Cow, Sheep, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Cytoskeleton preparation from HeLa cells, Application: IF, IHC, WB, FC, Size: 500 uL