Anti-CD86 Mouse Monoclonal Antibody (CF594) [clone: C86/1146]

Supplier: Biotium
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BNC941146-100 BNC941146-500
75908-354EA 205.77 USD
75908-354 75908-356
Anti-CD86 Mouse Monoclonal Antibody (CF594) [clone: C86/1146]
Antibodies
This antibody recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkins disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: CD86
Clonality: Monoclonal
Clone: Clone C86/1146
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: Mouse/IgG s
Reactivity: Human, Mouse, Rat
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