Anti-ZAP70 Mouse Monoclonal Antibody (CF594) [clone: ZAP70/528 + 2F3.2]

Supplier: Biotium

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BNC941137-100 BNC941137-500

75980-272EA 205.77 USD

75980-272 75980-274

Anti-ZAP70 Mouse Monoclonal Antibody (CF594) [clone: ZAP70/528 + 2F3.2]

Antibodies

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells.Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: ZAP70
Clonality: Monoclonal
Clone: Clone ZAP70/528 + 2F3.2
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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