Anti-PTPRC Mouse Monoclonal Antibody (CF488A) [clone: PTPRC/1131]

Supplier: Biotium
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BNC881131-100 BNC881131-500
75913-014EA 205.77 USD
75913-014 75913-016
Anti-PTPRC Mouse Monoclonal Antibody (CF488A) [clone: PTPRC/1131]
Antibodies
This antibody recognizes a protein of 205 kDa-220 kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4 T-cells, 50% of peripheral CD8 T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4 or CD8 T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO ve) from B cell lymphomas (CD45RA ve).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: Clone PTPRC/1131
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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