Anti-MCAM Mouse Monoclonal Antibody (CF488A) [clone: MUC18/1130]

Supplier: Biotium

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BNC881130-100 BNC881130-500

75964-136EA 205.77 USD

75964-136 75964-138

Anti-MCAM Mouse Monoclonal Antibody (CF488A) [clone: MUC18/1130]

Antibodies

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: Clone MUC18/1130
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human

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