Anti-MCAM Mouse Monoclonal Antibody (CF640R) [clone: MCAM/1101]

Supplier: Biotium

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BNC401101-100 BNC401101-500

75960-704EA 205.77 USD

75960-704 75960-706

Anti-MCAM Mouse Monoclonal Antibody (CF640R) [clone: MCAM/1101]

Antibodies

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: Clone MCAM/1101
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human

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