Anti-HLA-DRA Mouse Monoclonal Antibody (CF647) [clone: 169-1B5.2]

Supplier: Biotium
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BNC471096-100 BNC471096-500
75883-526EA 205.77 USD
75883-526 75883-528
Anti-HLA-DRA Mouse Monoclonal Antibody (CF647) [clone: 169-1B5.2]
Antibodies
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: HLA-DRA
Clonality: Monoclonal
Clone: Clone 169-1B5.2
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Cat, Cow, Human
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