Anti-CDH16 Mouse Monoclonal Antibody (CF488A) [clone: CDH16/1071]

Supplier: Biotium
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BNC881071-100 BNC881071-500
75955-968EA 205.77 USD
75955-968 75955-970
Anti-CDH16 Mouse Monoclonal Antibody (CF488A) [clone: CDH16/1071]
Antibodies
This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CDH16
Clonality: Monoclonal
Clone: Clone CDH16/1071
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Dog, Human, Mouse, Rabbit
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