Anti-PTPRC Mouse Monoclonal Antibody (CF568) [clone: DF-B1]

Supplier: Biotium
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BNC681066-100 BNC681066-500
75913-238EA 205.77 USD
75913-238 75913-240
Anti-PTPRC Mouse Monoclonal Antibody (CF568) [clone: DF-B1]
Antibodies
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: DF-B1
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG3, kappa
Reactivity: Human
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