Anti-CD3E Mouse Monoclonal Antibody (Biotin) [clone: CRIS-7]

Supplier: Biotium

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75895-422EA 205.77 USD

75895-422 75895-424

Anti-CD3E Mouse Monoclonal Antibody (Biotin) [clone: CRIS-7]

Antibodies

This antibody recognizes the epsilon-chain of CD3 (Workshop V; Code: CD03.09), which consists of five different polypeptide chains (designated as γ, δ, ε, ζ, and η) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Type: Primary
Antigen: CD3E
Clonality: Monoclonal
Clone: CRIS-7
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Monkey

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