Anti-TRIM29 Mouse Monoclonal Antibody (CF594) [clone: TRIM29/1042]

Supplier: Biotium
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BNC941042-100 BNC941042-500
75977-808EA 205.77 USD
75977-808 75977-810
Anti-TRIM29 Mouse Monoclonal Antibody (CF594) [clone: TRIM29/1042]
Antibodies
This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: TRIM29
Clonality: Monoclonal
Clone: TRIM29/1042
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human
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