Anti-CD22 Mouse Monoclonal Antibody (CF568) [clone: Myg13]

Supplier: Biotium
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BNC680974-100 BNC680974-500
75891-098EA 205.77 USD
75891-098 75891-100
Anti-CD22 Mouse Monoclonal Antibody (CF568) [clone: Myg13]
Antibodies
This antibody recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: CD22
Clonality: Monoclonal
Clone: Clone Myg13
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat
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