Anti-UACA Mouse Monoclonal Antibody (Biotin) [clone: AE-5]

Supplier: Biotium

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BNCB0956-100 BNCB0956-500

75978-768EA 205.77 USD

75978-768 75978-770

Anti-UACA Mouse Monoclonal Antibody (Biotin) [clone: AE-5]

Antibodies

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Type: Primary
Antigen: UACA
Clonality: Monoclonal
Clone: Clone AE-5
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse

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