Anti-PDCD1 Mouse Monoclonal Antibody (CF488A) [clone: PDCD1/922]

Supplier: Biotium
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BNC880922-100 BNC880922-500
75969-672EA 205.77 USD
75969-672 75969-674
Anti-PDCD1 Mouse Monoclonal Antibody (CF488A) [clone: PDCD1/922]
Antibodies
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: PDCD1
Clonality: Monoclonal
Clone: Clone PDCD1/922
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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