Anti-MYC Mouse Monoclonal Antibody [clone: MYC909]

Supplier: Biotium

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BNUB0909-100 BNUB0909-500

75921-180EA 240.92 USD

75921-180 75921-182

Anti-MYC Mouse Monoclonal Antibody [clone: MYC909]

Antibodies

This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL's) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas.

Type: Primary
Antigen: MYC
Clonality: Monoclonal
Clone: MYC909
Conjugation: Unconjugated
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgG1, kappa

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