Anti-CD34 Mouse Monoclonal Antibody (Biotin) [clone: QBEnd/10 HPCA1/763]

Supplier: Biotium

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BNCB0904-100 BNCB0904-500

75894-650EA 205.77 USD

75894-650 75894-652

Anti-CD34 Mouse Monoclonal Antibody (Biotin) [clone: QBEnd/10 HPCA1/763]

Antibodies

This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.

Type: Primary
Antigen: CD34
Clonality: Monoclonal
Clone: QBEnd/10 HPCA1/763
Conjugation: Biotin
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgGs

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