Anti-HSPB1 Mouse Monoclonal Antibody (CF488A) [clone: G3.1]

Supplier: Biotium
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BNC880861-100 BNC880861-500
75953-214EA 205.77 USD
75953-214 75953-216
Anti-HSPB1 Mouse Monoclonal Antibody (CF488A) [clone: G3.1]
Antibodies
This MAb reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated24Kprotein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian α-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: HSPB1
Clonality: Monoclonal
Clone: Clone G3.1
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Chicken, Chimpanzee, Human, Monkey, Mouse, Rat, Sheep
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