Anti-MUC1 Mouse Monoclonal Antibody (CF594) [clone: MUC1/845]

Supplier: Biotium
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BNC940845-100 BNC940845-500
75963-818EA 205.77 USD
75963-818 75963-820
Anti-MUC1 Mouse Monoclonal Antibody (CF594) [clone: MUC1/845]
Antibodies
In Western blotting, this antibody recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. The α subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The β subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: MUC1
Clonality: Monoclonal
Clone: Clone MUC1/845
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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