Anti-CNN1 Mouse Monoclonal Antibody (Biotin) [clone: CALP]

Supplier: Biotium
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BNCB0831-100 BNCB0831-500
75882-904EA 205.77 USD
75882-904 75882-906
Anti-CNN1 Mouse Monoclonal Antibody (Biotin) [clone: CALP]
Antibodies
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

Type: Primary
Antigen: CNN1
Clonality: Monoclonal
Clone: Clone CALP
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Rat
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