Anti-CD74 Mouse Monoclonal Antibody [clone: CLIP/813]

Supplier: Biotium

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BNUB0813-100 BNUB0813-500

75910-476EA 240.92 USD

75910-476 75910-502

Anti-CD74 Mouse Monoclonal Antibody [clone: CLIP/813]

Antibodies

This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).

Type: Primary
Antigen: CD74
Clonality: Monoclonal
Clone: Clone CLIP/813
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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