Anti-CHGA Mouse Monoclonal Antibody (CF405M) [clone: CHGA/798]

Supplier: Biotium
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BNC050798-100 BNC050798-500
75909-998EA 205.77 USD
75909-998 75910-000
Anti-CHGA Mouse Monoclonal Antibody (CF405M) [clone: CHGA/798]
Antibodies
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405M is a blue fluorescent dye (Ex/Em 408/452 nm) with superior brightness and photostability compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: Clone CHGA/798
Conjugation: CF405M
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Rat
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