Anti-IGKC Mouse Monoclonal Antibody (CF488A) [clone: HP6053 L1C1]

Supplier: Biotium
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BNC880755-100 BNC880755-500
75955-488EA 205.77 USD
75955-488 75955-490
Anti-IGKC Mouse Monoclonal Antibody (CF488A) [clone: HP6053 L1C1]
Antibodies
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: IGKC
Clonality: Monoclonal
Clone: Clone HP6053 L1C1
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
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