Anti-IGKC Mouse Monoclonal Antibody (CF405S) [clone: HP6053 L1C1]

Supplier: Biotium
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BNC040755-100 BNC040755-500
75955-484EA 205.77 USD
75955-484 75955-486
Anti-IGKC Mouse Monoclonal Antibody (CF405S) [clone: HP6053 L1C1]
Antibodies
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: IGKC
Clonality: Monoclonal
Clone: Clone HP6053 L1C1
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
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