Anti-MYC Mouse Monoclonal Antibody (Biotin) [clone: CT14.G4]

Supplier: Biotium

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BNCB0710-100 BNCB0710-500

75921-046EA 205.77 USD

75921-046 75921-048

Anti-MYC Mouse Monoclonal Antibody (Biotin) [clone: CT14.G4]

Antibodies

The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

Type: Primary
Antigen: MYC
Clonality: Monoclonal
Clone: Clone CT14.G4
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Chimpanzee, Gorilla, Human

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