Anti-MYC Mouse Monoclonal Antibody (CF488A) [clone: MYC699]

Supplier: Biotium
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BNC880699-100 BNC880699-500
75921-158EA 205.77 USD
75921-158 75921-160
Anti-MYC Mouse Monoclonal Antibody (CF488A) [clone: MYC699]
Antibodies
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: MYC
Clonality: Monoclonal
Clone: Clone MYC699
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chimpanzee, Gorilla, Human
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