Anti-MYC Mouse Monoclonal Antibody (CF405M) [clone: MYC699]

Supplier: Biotium
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BNC050699-500 BNC050699-100
75921-152EA 569.73 USD
75921-152 75922-206
Anti-MYC Mouse Monoclonal Antibody (CF405M) [clone: MYC699]
Antibodies
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405M is a blue fluorescent dye (Ex/Em 408/452 nm) with superior brightness and photostability compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: MYC
Clonality: Monoclonal
Clone: Clone MYC699
Conjugation: CF405M
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chimpanzee, Gorilla, Human
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