Anti-KDR Mouse Monoclonal Antibody [clone: KDR657]

Supplier: Biotium

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BNUB0657-100 BNUB0657-500

75979-254EA 240.92 USD

75979-254 75979-256

Anti-KDR Mouse Monoclonal Antibody [clone: KDR657]

Antibodies

CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Type: Primary
Antigen: KDR
Clonality: Monoclonal
Clone: Clone KDR657
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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