Anti-MUC1 Mouse Monoclonal Antibody (CF405S) [clone: VU-2G7]

Supplier: Biotium
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BNC040630-100 BNC040630-500
75963-538EA 205.77 USD
75963-538 75963-540
Anti-MUC1 Mouse Monoclonal Antibody (CF405S) [clone: VU-2G7]
Antibodies
MAb VU-2G7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with epitope fingerprinting. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: MUC1
Clonality: Monoclonal
Clone: Clone VU-2G7
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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