Anti-CHGA Mouse Monoclonal Antibody (Biotin) [clone: PHE5]

Supplier: Biotium

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BNCB0461-100 BNCB0461-500

75909-238EA 205.77 USD

75909-238 75909-240

Anti-CHGA Mouse Monoclonal Antibody (Biotin) [clone: PHE5]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: Clone PHE5
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Monkey

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