Anti-CD3E Rabbit Polyclonal Antibody (CF640R)

Supplier: Biotium
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BNC400385-100 BNC400385-500
75980-456EA 205.77 USD
75980-456 75980-458
Anti-CD3E Rabbit Polyclonal Antibody (CF640R)
Antibodies
This antibody recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: CD3E
Clonality: Polyclonal
Clone:
Conjugation: CF640R
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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