Anti-MS4A1 Mouse Monoclonal Antibody (CF568) [clone: 109-3C2]

Supplier: Biotium
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BNC680355-100 BNC680355-500
75890-498EA 205.77 USD
75890-498 75890-500
Anti-MS4A1 Mouse Monoclonal Antibody (CF568) [clone: 109-3C2]
Antibodies
This antibody recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It This antibody recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: Clone 109-3C2
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG3, kappa
Reactivity: Human
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