Anti-NKX2-2 Mouse Monoclonal Antibody (CF647) [clone: NX2/294]

Supplier: Biotium

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BNC470294-100 BNC470294-500

75966-264EA 205.77 USD

75966-264 75968-594

Anti-NKX2-2 Mouse Monoclonal Antibody (CF647) [clone: NX2/294]

Antibodies

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: NKX2-2
Clonality: Monoclonal
Clone: Clone NX2/294
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Chicken, Human, Mouse, Rat

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