Anti-ERBB2 Mouse Monoclonal Antibody (CF488A) [clone: HRB2/258]

Supplier: Biotium
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BNC880258-100 BNC880258-500
75953-032EA 205.77 USD
75953-032 75953-034
Anti-ERBB2 Mouse Monoclonal Antibody (CF488A) [clone: HRB2/258]
Antibodies
This antibody recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. C-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: ERBB2
Clonality: Monoclonal
Clone: Clone HRB2/258
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Rat
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