Anti-CD2 Mouse Monoclonal Antibody [clone: 1E7E8.G4]

Supplier: Biotium

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BNUB0249-100 BNUB0249-500

75890-116EA 240.92 USD

75890-116 75890-118

Anti-CD2 Mouse Monoclonal Antibody [clone: 1E7E8.G4]

Antibodies

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Type: Primary
Antigen: CD2
Clonality: Monoclonal
Clone: Clone 1E7E8.G4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human

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