Anti-CD2 Mouse Monoclonal Antibody (CF640R) [clone: 1E7E8.G4]

Supplier: Biotium
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BNC400249-100 BNC400249-500
75889-918EA 205.77 USD
75889-918 75889-920
Anti-CD2 Mouse Monoclonal Antibody (CF640R) [clone: 1E7E8.G4]
Antibodies
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: CD2
Clonality: Monoclonal
Clone: Clone 1E7E8.G4
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
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