Anti-PTH Mouse Monoclonal Antibody (CF555) [clone: 3H9]

Supplier: Biotium
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BNC550242-100 BNC550242-500
75973-292EA 205.77 USD
75973-292 75973-294
Anti-PTH Mouse Monoclonal Antibody (CF555) [clone: 3H9]
Antibodies
The epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®555 is a bright orange-red fluorescent dye (Ex/Em 555/565 nm) that is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: PTH
Clonality: Monoclonal
Clone: Clone 3H9
Conjugation: CF555
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human
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