Anti-TLR2 Mouse Monoclonal Antibody (Biotin) [clone: TLR2/221]

Supplier: Biotium

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BNCB0221-100 BNCB0221-500

75891-902EA 205.77 USD

75891-902 75891-904

Anti-TLR2 Mouse Monoclonal Antibody (Biotin) [clone: TLR2/221]

Antibodies

This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Type: Primary
Antigen: TLR2
Clonality: Monoclonal
Clone: Clone TLR2/221
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Dog, Human, Monkey

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