Anti-ICAM3 Mouse Monoclonal Antibody (CF594) [clone: 101-1D2]

Supplier: Biotium
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BNC940177-100 BNC940177-500
75911-952EA 205.77 USD
75911-952 75911-954
Anti-ICAM3 Mouse Monoclonal Antibody (CF594) [clone: 101-1D2]
Antibodies
This antibody recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: ICAM3
Clonality: Monoclonal
Clone: Clone 101-1D2
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
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