Anti-CD27 Mouse Monoclonal Antibody (CF405S) [clone: 203.6]

Supplier: Biotium
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BNC040163-100 BNC040163-500
75891-594EA 205.77 USD
75891-594 75891-596
Anti-CD27 Mouse Monoclonal Antibody (CF405S) [clone: 203.6]
Antibodies
This antibody recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CD27
Clonality: Monoclonal
Clone: Clone 203.6
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG3, kappa
Reactivity: Human
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