Anti-MS4A1 Mouse Monoclonal Antibody (CF568) [clone: B9E9]

Supplier: Biotium
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BNC680160-100 BNC680160-500
75890-618EA 205.77 USD
75890-618 75890-620
Anti-MS4A1 Mouse Monoclonal Antibody (CF568) [clone: B9E9]
Antibodies
This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 This antibody recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: Clone B9E9
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
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