Anti-BCL2 Mouse Monoclonal Antibody (Biotin) [clone: 100/D5]

Supplier: Biotium

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BNCB0045-100 BNCB0045-500

75884-562EA 205.77 USD

75884-562 75884-564

Anti-BCL2 Mouse Monoclonal Antibody (Biotin) [clone: 100/D5]

Antibodies

This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.

Type: Primary
Antigen: BCL2
Clonality: Monoclonal
Clone: Clone 100/D5
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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