Anti-MUC5AC Mouse Monoclonal Antibody [clone: 45M1]

Supplier: Biotium
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BNUB0031-100 BNUB0031-500
75962-488EA 240.92 USD
75962-488 75962-490
Anti-MUC5AC Mouse Monoclonal Antibody [clone: 45M1]
Antibodies
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: MUC5AC
Clonality: Monoclonal
Clone: Clone 45M1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Cat, Chicken, Hedgehog, Human, Monkey, Mouse, Pig, Rabbit, Rat
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