Anti-MLANA Mouse Monoclonal Antibody (Biotin) [clone: M2-7C10]

Supplier: Biotium

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BNCB0009-100 BNCB0009-500

75963-020EA 205.77 USD

75963-020 75963-022

Anti-MLANA Mouse Monoclonal Antibody (Biotin) [clone: M2-7C10]

Antibodies

This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Type: Primary
Antigen: MLANA
Clonality: Monoclonal
Clone: Clone M2-7C10
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Horse, Human

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