Anti-CCND1 Mouse Monoclonal Antibody (CF568) [clone: DCS-6]

Supplier: Biotium
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: 0.0 out of 5

BNC680007-500 BNC680007-100
75924-634EA 569.73 USD
75924-634 75925-096
Anti-CCND1 Mouse Monoclonal Antibody (CF568) [clone: DCS-6]
Antibodies
This antibody recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: CCND1
Clonality: Monoclonal
Clone: Clone DCS-6
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Monkey, Mouse, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR