Mouse Recombinant Angiopoietin (from HEK293 cells)

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-40B-0131-C010 AG-40B-0131-3010

102980-238EA 263.08 USD

102980-238 102980-240

Mouse Recombinant Angiopoietin (from HEK293 cells)

Proteins and Peptides

Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.

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