Mouse Recombinant PEDF (from CHO Cells)

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-40B-0118-C010 AG-40B-0118-3010

102980-192EA 318.46 USD

102980-192 102980-194

Mouse Recombinant PEDF (from CHO Cells)

Proteins and Peptides

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

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