N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95% (by HPLC)

Supplier: SAFE AND SURE NEDERLAND B.V.

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Total Ratings: 0
Avg. Ratings: 0.0 out of 5

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CHM157-0005 CHM157-0050

76003-112EA 70.9 USD

76003-112 76003-114

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95% (by HPLC)

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride

EGFR tyrosine kinase auto-phosphorylation inhibitor

Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC50 of 2 nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl.

Formula: C₂₂H₂₄ClN₃O₄

MDL Number: MFCD07781272
CAS Number: 183319-69-9

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